Insulin resistance was present in the patients with type 2 diabetes, as evidenced by the clamp data (table 1) and supported by the presence of hyperglycemia (Table 2; Figure 3), elevated HbA1c (Table 1), and a tendency to reduced adiponectin concentrations (main effect, p = 0.0643) in T2DM compared with OB (Table 2). This evidence concerns the gene ADIPOQ and type 2 diabetes mellitus.