For the test set samples, additional data were obtained for 4 conventional serum tumor markers, CYFRA21-1, CEA, SCCA, and NSE, and a binary logistic regression model was developed for these 4 markers, which had an AUC of 0.6948, a sensitivity of 33.56% at 90% specificity, and a sensitivity of 46.98% at 80% specificity (Figure 9B). The gene discussed is ENO2; the disease is neoplasm.