Very recently Shiau and colleagues reported a positive association between FAK and VEGFR2 in TNBC patients and demonstrated that FAK knockdown inhibited endothelial tube formation in a zebrafish model; in addition, they also showed in a mice xenograft model that FAK inhibitors could suppress tumor growth and tumor vascular formation via VEGFR2 and VEGF downregulation (58). The gene discussed is PTK2; the disease is neoplasm.