Most parameters such as heart rate, fever, weight loss, massive PE, mediastinal lymph node enlargement, pleural effusion, CEA, effusion LDH, effusion CEA, TP, ADA, effusion ADA, and effusion GLU were significantly different between MPE and BPE groups in the training set (Supplementary Table S1). Here, CEACAM5 is linked to Pleural effusion.