MYC and cancer: (72) investigated that miR-105 could be induced by oncoprotein MYC in cancer cells and activate MYC signaling in CAF to promote metabolic reprogramming through the following mechanisms: a, suppressing ecotropic energy consumption while supplying cancer cells; b, energy-rich metabolites(such as acetate, glutamate) from ecotropic cells promote anabolic cancer cells; c, neighboring ecotropic cells convert metabolic by-products produced by cancer into non-toxic.