Although we did not observe any differences in CD8+ or Foxp3+ cell populations in breast tumours with high or low PDLIM2 expression, the association of high PDLIM2 expression with M2 macrophage infiltration, and the association of this immune subset with breast cancer aggressiveness suggests that the presence of PDLIM2 in TNBC could influence the overall tumour microenvironment. Here, PDLIM2 is linked to breast cancer.