CHEK2 and ovarian carcinoma: Apart from BRCA1/2 germline mutations that predominate in HGSC, other germline mutations were reported in HR genes: (2%) in BARD1, 4 (4.5%) in BRIP1, 1 (1%) in CHEK1, 3 (3%) in CHEK2, 2 (2%) in FAM175A, 1 (1%) in NBN, 2 (2%) in PALB2, 3 (3%) in RAD51C and 4 (4.5%) in RAD51D. Recent literature supports that up to 24% of ovarian cancers are associated with germline mutations, and of these, 29% harbor mutations in genes other than BRCA1/2 (9).