HRR alterations involve Fanconi anemia genes (PALB2, FANCA, FANCL, FANCI, FANCC), core RAD genes (RAD50, RAD51, RAD51B, RAD51C) as well as DNA damage response genes (ATM, ATR, CHEK1, CHEK2) (10). The gene discussed is RAD51B; the disease is Fanconi anemia.