For the two good ARGs, DAPK1, as a regulator of autophagy and apoptosis, is reported to function as a tumor-suppressor in various cancers (26), and has been reported to contribute to neuronal apoptosis due to ischemia reperfusion injury in mouse NB cell line N2a cells (27, 28); ULK2 has not been reported in NB, however, it has been reported to be required for proper projection of axons in the forebrain (29), indicating a tumor-suppressive role for NB. This evidence concerns the gene ULK2 and neuroblastoma.