To our knowledge, 5 genes TWIST1, SNAI2, TSHR, FOXE1, and CD274 (PD-L1) have been reported to be differentially expressed in ATC compared to normal thyroid samples and other thyroid cancer samples and one gene (E2F7) has been identified in ATC but without confirmation in clinical samples (20) or without comparisons to other thyroid carcinomas (57). This evidence concerns the gene SNAI2 and thyroid cancer.