Analysis of the GEO (GSE15471) database revealed that COL10A1 was differentially expressed in pancreatic cancer versus normal tissue (Figure 1A) and that COL10A1 was highly expressed in tumor tissues compared with normal tissues of PDAC patients in the GEPIA dataset (Figure 1B and Supplementary Figure 1A). This evidence concerns the gene COL10A1 and pancreatic neoplasm.