Our study also confirmed that simultaneous CSM-TACE and PSE using 8spheres® can increase the level of cholinesterase, suggesting that CSM-TACE+PSE can improve liver functional reserve capacity by improving hemodynamics (24), which is particularly important for the prognosis of patients with advanced HCC and therefore an important factor in achieving a good prognosis. Here, BCHE is linked to hepatocellular carcinoma.