We also constructed a possible protein-protein interaction (PPI) network to study the mechanism of TUBGCP4 in HCC and concluded that TUBGCP4 was closely related to the expression of nonmetastatic cells 7 (NME7), polo-like kinase 4 (PLK4), and other proteins in HCC (Figure 3(c)). This evidence concerns the gene PLK4 and hepatocellular carcinoma.