In the same way, Trang et al. (24) showed in 64 RA patients increased 18F-FDG uptake of the aortic wall after 6 months of biologic therapies (TNF inhibitors, IL6 blockers and Ig CTLA4), even in RA patients with low disease activity or in clinical remission. The gene discussed is IL6; the disease is rheumatoid arthritis.