In the female participants (n = 77,785), age (per 1 year; OR = 1.004; p = 0.002), hypertension history (OR = 0.855; p < 0.001), BMI (per 1 kg/m2; OR = 1.015; p < 0.001), triglycerides (per 1 mg/dL; OR = 0.997; p < 0.001), total cholesterol (per 1 mg/dL; OR = 0.997; p < 0.001), AST (per 1 U/L; OR = 1.010; p < 0.001), ALT (per 1 U/L; OR = 1.008; p < 0.001), eGFR (per 1 mL/min/1.73 m2; OR = 0.997; p < 0.001), and uric acid (per 1 mg/dL; OR = 0.922; p < 0.001) were significantly associated with HBV infection. Here, GPT is linked to Hypertension.