In terms of KEGG Pathway, these genes were mainly enriched in MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, EGFR tyrosine kinase inhibitor resistance, Rap1 signaling pathway, Ras signaling pathway, Central carbon metabolism in cancer, ErbB signaling pathway, Signaling pathways regulating pluripotency of stem cells and Regulation of actin cytoskeleton. The gene discussed is AKT1; the disease is cancer.