The frequencies of the CCT haplotype of HSP70-1 (rs1008438-rs562047-rs12190359) and the ACCCTTT haplotype of HSP70 (rs2227956-rs1043618-rs1008438-rs562047-rs12190359-rs2763979-rs6457452) were significantly lower in PSS patients than those in healthy controls (0.33% vs. 3.28%, P = 0.006, Pc = 0.024, and OR = 0.10; 0.34% vs. 3.32%, P = 0.006, Pc = 0.048, and OR = 0.10, respectively; Table 3). The gene discussed is HSPA1B; the disease is peeling skin syndrome.