The frequencies of the CCT haplotype of HSP70-1 gene (rs1008438-rs562047-rs12190359) and the ACCCTTT haplotype of HSP70 gene (rs2227956-rs1043618-rs1008438-rs562047-rs12190359-rs2763979-rs6457452) were significantly lower in PSS patients than those in healthy controls (Pc = 0.024, OR = 0.10; Pc = 0.048, OR = 0.10, respectively). This evidence concerns the gene HSPA1B and peeling skin syndrome.