For example, the gene PLAGL1 is associated with neonatal diabetes mellitus [54]; FAM3C is a therapeutical target for type 2 diabetes and non-alcoholic fatty liver disease [55]; OAZ2 is differentially methylated in children exposed to maternal diabetes in utero versus unexposed [56]; HEG1 is a regulator of heart and vessel formation [57]; and DECR2 is involved in lipid metabolism [58], which might also be related to diabetes [59]. This evidence concerns the gene HEG1 and diabetes mellitus.