The network analysis of the selected enriched genes from DR_Set_2 showed pathways such as Wnt signalling, hippo signalling, calcium signalling, p53 signalling, thyroid hormone signalling, MAPK signalling, RNA polymerase, RNA transport, protein export, spliceosome, ribosome, purine metabolism, retinol metabolism, lipoic acid metabolism, arginine and proline metabolism, amino sugar and nucleotide sugar metabolism, steroid hormone biosynthesis, cytokine–cytokine receptor interaction, bacterial invasion of epithelial cells, vasopressin- regulated water reabsorption, African trypanosomiasis. The gene discussed is TP53; the disease is human African trypanosomiasis.