CD44 and breast cancer: Our transcriptomic analyses showed that two subpopulations of CSCs co-exist in GC, based on their EMT profile as described by Wicha’s group in breast cancer [29], but defined by different CSCs markers: panCD44+ CSCs expressed a proliferative and an epithelial MET-like signature similarly to ALDH+ CSCs in breast cancer [29], and CD44v3+ CSCs harboured an EMT-like signature like CD44+ breast CSCs [29].