Moreover, subjects in the multi-vessel CAD group exhibited significantly higher HbA1c, FPG, TG, LAD, IVS, LVPW, BNP, TyG index, TyG-BMI index, TG/HDL-C ratio and METS-IR than their counterparts in the single-vessel group (all P < 0.05). The gene discussed is NPPB; the disease is coronary artery disorder.