Of note, the brain of this 83-year-old female also showed subacute infarct, neuronophagia, CD8 + and CD4 + T lymphocytes, and age-related chronic pathology including AD, neocortical Lewy body disease, atherosclerosis, and chronic infarcts (patient #19, Tables 2 and 3). This evidence concerns the gene CD8A and Alzheimer disease.