We also observed the induction of genes encoding secreted pro-inflammatory mediators, mainly chemokines, such as CXCL7 (also named pro-plateletbasicprotein, PPBP), CLL7, CXCL5 and CXCL8. CXCL7/PPBP is a fatty acid-induced chemokine elevated in atherosclerosis; CCL7 is a macrophage foam cell marker [30] recruiting monocytes to sites of inflammation and has a high affinity to CCR2. Here, CXCL8 is linked to atherosclerosis.