Alternatively, the tissues that are not representative can be eliminated from the further downstream analyses that may result in variable tissue numbers across different groups.[24] For instance, in the CK8/18 staining of the BC‐5 samples in our study, it is hard to gauge if the chosen tissue sections/microtissues themselves were more stromal than glandular or if it was representative of the patient's inherent tissue characteristics. This evidence concerns the gene KRT8 and breast cancer.