LGALS9 and colorectal carcinoma: As shown in Fig. 1A, the analysis of TCGA RNA-seq data using the TIMER database showed that galectin-9 mRNA expression was significantly downregulated in CRC compared with normal tissues.Then, we downloaded data from the LinkedOmics Database to analyze the relationship between galectin-9 mRNA (LGALS9) expression and clinicopathological factors.