However, there was no apparent family history of parkinsonism or dementia in all enrolled IPD patients, with a later mean age of onset in the enrolled IPD patients that was 67.2 years in cohort A and 65.2 years in cohort C. Elevated plasma GlcCer levels have recently been reported in GBA1 mutation carriers of IPD. Here, GBA1 is linked to Parkinsonism.