IFNA1 and neoplasm: JQ1 has previously been reported to directly inhibit transcription of IFN-response genes (Gibbons et al., 2019; Gusyatiner et al., 2021) suggesting this may be due to the direct action of JQ1 within our tumour cells; however, JQ1-dependent changes to the tumour microenvironment may also influence these expression pathways.