CXCL10, CXCL5, MMP1, CXCL12, CXCL11, CXCL2, STAT1, IL‐6 and TLR2 were hub genes in network and may promote or inhibit the homing or of immune cells in tumours and immune cell differentiation, bring intratumoral immune heterogeneity. This evidence concerns the gene TLR2 and neoplasm.