CXCL10, CXCL5, MMP1, CXCL12, CXCL11, CXCL2, STAT1, IL‐6 and TLR2 were hub genes in network and may promote or inhibit the homing or of immune cells in tumours and immune cell differentiation, bring intratumoral immune heterogeneity. The gene discussed is CXCL12; the disease is neoplasm.