CXCL10, CXCL5, MMP1, CXCL12, CXCL11, CXCL2, STAT1, IL‐6 and TLR2 were hub genes in network and may promote or inhibit the homing or of immune cells in tumours and immune cell differentiation, bring intratumoral immune heterogeneity. Here, MMP1 is linked to neoplasm.