To interrogate the relationship between the methylation status of DUSP13 and the expression level of DUSP13 in HCC specimens, we performed correlation analysis and found four methylation sites (cg11709896, cg19532743, cg17292610, and cg04834572) were significant inversely proportional to DUSP13 expression (Figure 6D). This evidence concerns the gene DUSP13B and hepatocellular carcinoma.