However, we found significant correlations of DUSP13 and immune infiltration in CD8 T cell (p < 0.001), resting memory CD4 T cell (p = 0.007), naïve B cell (p = 0.011), and macrophage M1 (p = 0.014) regarding the MVI but not in the non‐MVI group, indicating that PVT1/DUSP13 axis may promote the MVI process via interaction with these immune infiltrating cells in HCC. The gene discussed is PVT1; the disease is hepatocellular carcinoma.