Tumors of various types exhibit abnormal activation of STAT family members, including ovarian cancer (9), breast cancer (10), prostate cancer, and (11) hematological and head and neck cancer (12), of which have been confirmed to be involved in angiogenesis, invasion, and metastasis of tumor cells, as well as their escape from the immune system. The gene discussed is SOAT1; the disease is ovarian carcinoma.