To be more specific, TNFSF4, CD86, PDCD1LG2, TNFRSF4, HAVCR2, CD28, TNFSF18, TNFRSF9, PTPRC, PDCD1, IL12B, CD80, JAK1were significantly highly expressed in gastric tumor tissues and cluster II that associated with worse OS. Here, PDCD1 is linked to gastric neoplasm.