found that among the GSDM family, only GSDMD gene expression was positively correlated with CD8+ T cell marker genes in cytotoxic T lymphocytes (CTLs) across LUAD, LUSC, and melanoma tumor samples in The Cancer Genome Atlas (TCGA) cohorts, suggesting that the function of GSDMD gene could be related with CD8+ T cells. This evidence concerns the gene GSDMD and melanoma.