ALK and non-small cell lung carcinoma: Epidermal growth factor gene, EGFR-mutation is the most common driver mutation, found in approximately 15% of NSCLC, and 5% are diagnosed with an anaplastic lymphoma kinase, ALK-alteration (1), although incidence varies by ethnicity (eg. around 30% EGFR mutations in the Asian NSCLC population (2)).