According to the data from numerous nations, the presence of Fn in CRC is significantly connected with the molecular characteristics of high microsatellite instability (MSI-H), high CpG island methylator phenotype (CIMP-H), BRAF mutation, TP53 wild type, consensus molecular subtypes 1 (CMS1) (Table 1). The gene discussed is BRAF; the disease is colorectal carcinoma.