The reduced dual phosphorylation of MPK3 and MPK6 in single and double mutants 30 min after inoculation (Figure 1A) prompted us to test whether ALD1, NPR1, and ICS1/SID2 control basal defense responses to PstDC3000 ΔAvrPto/ΔAvrPtoB infection. The gene discussed is NPR1; the disease is infection.