The recent research on α-synuclein associated diseases suggests that PD, DLB, and MSA, where the misfolding of α-synuclein monomers into oligomers followed by progressive transformation of oligomers into amyloid fibrils takes place, have become a central point of current synucleinopathy research (Oliveira et al., 2021). Here, SNCA is linked to multiple system atrophy.