Histology (pooled proportion of patients with improve)• Steatosis: 88% (95% CI: 0.80-0.94)• Steatohepatitis: 59% (95% CI: 0.38 -0.78)• Fibrosis: 30% (95% CI: 0.21 -0.41)Biochemistry (pooled proportion of patients with improve)• AST 32% (95% CI:0.22-0.42)• ALT 62% (95% CI: 0.42 - 0.82)• ALP 45% (95% CI: 0.19- 0.71). This evidence concerns the gene GPT and fibrosis.