Recently, the REVITA-1 study results associated DMR with long term improvements in insulin sensitivity and other glycemic parameters, such as HbA1c, after 24 months in DM patients; although liver parameters are not a specific outcome, a decrease in ALT and triglycerides levels was observed (65); with these promising results in metabolic parameters, studies about the benefits of DMR on NAFLD are needed to recommend this endoscopic technique as a therapeutic option. This evidence concerns the gene GPT and diabetes mellitus.