As shown in Table 1, the kidney function and lipid indicators of NGAL, Cr, CysC, eGFR, triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and apolipoprotein B (Apo-B) were statistically significant among the HC, RCC and BKT groups (all p < 0.05). The gene discussed is LCN2; the disease is beta-ketothiolase deficiency.