We first performed consensus clustering analysis based on 23 differentially expressed NET-related genes (SELPLG, LILRB2, ITGB2, CSF3R, ITGAM, TLR2, CREB5, TLR7, DYSF, TLR8, MMP9, CYBB, PTAFR, SIGLEC14, FPR1, SLC22A4, DNASE1, MTOR, CYP4F3, F3, SELP, KCNJ15, and G0S2) in ccRCC. The gene discussed is CREB5; the disease is nonpapillary renal cell carcinoma.