In HCC cells, MEG3 overexpression can sponge out miR-9-5p and upregulate the expression of SOX11, and then observe apoptosis-related changes of Bcl-2 and caspase-3, suggesting that MEG3 can promote the apoptosis of HCC cells (Liu et al., 2019b). The gene discussed is SOX11; the disease is hepatocellular carcinoma.