An iTRAQ-based proteomic analysis in combination with western blotting (WB) revealed that ginsenoside F2 induced autophagic cell death in the human gastric carcinoma cell line SGC7901 via an increase in Atg5, Atg7, Atg10, and PUMA, the ribosomal protein-p53 signaling pathway, and Beclin-1, UVRAG, and AMBRA-1, important molecules in the Bcl-xl/Beclin-1 pathway (Mao et al., 2016). The gene discussed is BECN1; the disease is gastric carcinoma.