Next, KEGG enrichment analysis performed for the two networks revealed that molecules in the PBS syndrome network were enriched in the IL-17 signaling pathway, rheumatoid arthritis, viral protein interaction with cytokine and cytokine receptor, Chagas disease, TNF signaling pathway, malaria, lipid and atherosclerosis, AA metabolism, and so forth (q-value > 0.05). The gene discussed is TNF; the disease is Chagas disease.