In addition, we also found that the top 6 binding energies from low to high were AKT1 and stigmasterol, quercetin, kaempferol, hederagenin, calycosin, and beta-sitosterol, respectively, which demonstrated that AKT1 may be a very critical target for ADI in the treatment of NSCLC. The gene discussed is AKT1; the disease is non-small cell lung carcinoma.