Based on clinicopathological data, it can be concluded that a significant linear relationship exists between the increasing grade of cervical intraepithelial neoplasia (CIN) leading to cervical carcinoma and the intensity of cytoplasmic NF-κB expression which suggests a tumor-promoting role for NF-κB in cervical cancer [34]. This evidence concerns the gene NFKB1 and cervical intraepithelial neoplasia.