JUN and melanoma: As shown in Fig. 3E-G, Additional file 2: Fig. S4C-E and Fig. S5D-E, AIL had no significant effect on c-Jun transcription (Fig. 3E and Additional file 2: Fig. S4C) but reduced c-Jun protein expression in a dose-dependent and time-dependent manner in melanoma cells (Fig. 3F-G, Additional file 2: Fig. S4D-E and Fig. S5D-E).