What is important, none of the specific ncRNA that was found to be significantly dysregulated in OPLL (miR-10a, miR-563, miR-199b, miR-182, miR-615, miR-132, lncR MALAT1, and lncR XIST) was investigated in other types of HO or its animal model [28]. The gene discussed is MALAT1; the disease is ossification of the posterior longitudinal ligament of the spine.