RT-qPCR results showed that the mRNA expression of CD19 (BCR signaling pathway), CD22 (BCR signaling pathway), and CD72 (BCR signaling pathway) was relatively lower in PBL than in DLBCL (Fig. 4A–C), while the expression of SDC1 (Cell adhesion molecule), CHRM3 (calcium signaling pathway), and HTR2C (calcium signaling pathway) was relatively higher in PBL than in DLBCL (Fig. 4D–F). The gene discussed is CD22; the disease is diffuse large B-cell lymphoma.