EMT was regulatedby ESM1 in tumor invasion of colorectal cancer through the activation of the NF-κB pathway [27].In addition, non-small-cell lung cancer proliferation, stemness, and EMT were regulated by ESM1/HIF-1α pathway [26].The expression and potential functions of ESM1 in cervical cancer have not been studiedthus far. Here, NFKB1 is linked to colorectal cancer.