Immunofluorescence staining of NSCLC tissues from the study participants (S4 Table) showed that the rate of positive AIF-1 expression was significantly higher for patients with positivity for IL-6 expression (P < 0.01 vs. no IL-6 expression) and positivity for VEGF expression (P < 0.05 vs. no VEGF expression). The gene discussed is IL6; the disease is non-small cell lung carcinoma.