Diagnostic work-up with bronchoscopy, endobronchial ultrasound (EBUS), computed tomography (CT) thorax, ultrasound (US) or CT abdomen, thoracocentesis, thoracoscopy, transthoracal biopsy and CT or MRI brain and, in adenocarcinomas, testing for epidermal growth factor receptor (EGFR) mutation were evenly performed across all groups (Table 2). The gene discussed is EGFR; the disease is adenocarcinoma.