There were no differences in gene or protein expression of PERK, p-eIF2α or ATF4 between pCLD and AIH livers (Fig 5C and 5D), though protein expression of p-eIF2α and ATF4 was increased in AIH samples (and pCLD samples as previously shown in Fig 3A and 3B) compared to controls, suggestive of ongoing ER stress (Fig 5D). The gene discussed is ATF4; the disease is autoimmune hepatitis.