EIF2AK3 and autoimmune hepatitis: There were no differences in gene or protein expression of PERK, p-eIF2α or ATF4 between pCLD and AIH livers (Fig 5C and 5D), though protein expression of p-eIF2α and ATF4 was increased in AIH samples (and pCLD samples as previously shown in Fig 3A and 3B) compared to controls, suggestive of ongoing ER stress (Fig 5D).